2-Amino-9-[(2R,4S,5S)-4-amino-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
3'-Amino-2',3'-dideoxyguanosine
CAS: 66323-49-7
Molecular Formula: C10H14N6O3
2-Amino-9-[(2R,4S,5S)-4-amino-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one - Names and Identifiers
| Name | 3'-Amino-2',3'-dideoxyguanosine |
| Synonyms | 3'-NH2-ddG 3'-AMINO-2'-DEOXY-D- GUANOSINE 3'-AMINO-2',3'-DIDEOXYGUANOSINE 3'-Amino-2',3'-dideoxyguanosine Guanosine,3'-aMino-2',3'-dideoxy- 3'-Amino-2',3'-dideoxy-D-guanosine 9-(3-Amino-2,3-dideoxy-β-D-ribofuranosyl)guanine 2-Amino-9-[(2R,4S,5S)-4-amino-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one 2-amino-9-[(2R,4S,5S)-4-amino-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6 -one 2-Amino-9-((2R,4S,5S)-4-amino-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one |
| CAS | 66323-49-7 |
| InChI | InChI=1/C10H14N6O3/c11-4-1-6(19-5(4)2-17)16-3-13-7-8(16)14-10(12)15-9(7)18/h3-6,17H,1-2,11H2,(H3,12,14,15,18)/t4-,5+,6+/m0/s1 |
2-Amino-9-[(2R,4S,5S)-4-amino-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one - Physico-chemical Properties
| Molecular Formula | C10H14N6O3 |
| Molar Mass | 266.26 |
| Density | 2.08g/cm3 |
| Boling Point | 662.4°C at 760 mmHg |
| Flash Point | 354.4°C |
| Water Solubility | Soluble in water (50 mg/ml). |
| Vapor Presure | 1.88E-18mmHg at 25°C |
| Appearance | Powder |
| Color | Off-white to Yellow |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.935 |
| MDL | MFCD09750824 |
2-Amino-9-[(2R,4S,5S)-4-amino-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one - Introduction
3 '-Amino-2',3 '-dideoxyguanosine is a nucleoside analog with the formula C10H15N5O3. The following is a detailed description of its nature, use, preparation and safety information:
Nature:
- 3 '-Amino-2',3 '-dideoxyguanosine is a white to pale yellow crystalline solid.
-It is insoluble in water, but soluble in some organic solvents, such as methanol and dimethyl sulfoxide.
-It is stable to heat and light, but easily degraded under acidic conditions.
Use:
- 3 '-Amino-2',3 '-dideoxyguanosine is commonly used to study the structure and function of RNA.
-It can be used as a probe for interaction with RNA to study the interaction mechanism between RNA and proteins, drugs, etc.
-Because it is a dideoxynucleoside, it can also be used to study the synthesis and degradation of DNA or RNA.
Preparation Method:
- 3 '-Amino-2',3 '-dideoxyguanosine is usually prepared by chemical synthesis.
-The specific preparation method includes the amination reaction of 2 ',3'-dideoxyguanosine to introduce an amino group into the 3 'position of the nucleoside.
Safety Information:
- 3 '-Amino-2',3 '-dideoxyguanosine is generally considered to have low toxicity under conventional conditions.
-Follow the laboratory's safe practices during operation, including wearing appropriate personal protective equipment.
-Hazardous environments such as exposure to heat, fire and strong acids should be avoided.
Nature:
- 3 '-Amino-2',3 '-dideoxyguanosine is a white to pale yellow crystalline solid.
-It is insoluble in water, but soluble in some organic solvents, such as methanol and dimethyl sulfoxide.
-It is stable to heat and light, but easily degraded under acidic conditions.
Use:
- 3 '-Amino-2',3 '-dideoxyguanosine is commonly used to study the structure and function of RNA.
-It can be used as a probe for interaction with RNA to study the interaction mechanism between RNA and proteins, drugs, etc.
-Because it is a dideoxynucleoside, it can also be used to study the synthesis and degradation of DNA or RNA.
Preparation Method:
- 3 '-Amino-2',3 '-dideoxyguanosine is usually prepared by chemical synthesis.
-The specific preparation method includes the amination reaction of 2 ',3'-dideoxyguanosine to introduce an amino group into the 3 'position of the nucleoside.
Safety Information:
- 3 '-Amino-2',3 '-dideoxyguanosine is generally considered to have low toxicity under conventional conditions.
-Follow the laboratory's safe practices during operation, including wearing appropriate personal protective equipment.
-Hazardous environments such as exposure to heat, fire and strong acids should be avoided.
Last Update：2024-04-09 21:04:16
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Product Name: 3'-Amino-2',3'-dideoxyguanosine Visit Supplier Webpage Request for quotation
CAS: 66323-49-7
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Mobile: 18021002903
QQ: 3008007409
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CAS: 66323-49-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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